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  • Featured Product
  • KD/KO Validated

CoraLite® Plus 488-conjugated PARK2/Parkin Polyclonal antibody

PARK2/Parkin Polyclonal Antibody for IF

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IF

Conjugate

CoraLite® Plus 488 Fluorescent Dye

Cat no : CL488-14060

Synonyms

AR JP, LPRS2, PARK2, Parkinson disease protein 2, PDJ, PRKN

Validation Data Gallery

Applications:
  • IF Staining of mouse heart using CL488-14060

    IF Staining of mouse heart using CL488-14060

    Immunofluorescent analysis of (4% PFA) fixed mouse heart tissue using CoraLite® Plus 488 PARK2/Parkin antibody (CL488-14060) at dilution of 1:200.

  • IF Staining of mouse heart using CL488-14060

    IF Staining of mouse heart using CL488-14060

    Immunofluorescent analysis of (4% PFA) fixed mouse heart tissue using CoraLite® Plus 488 PARK2/Parkin antibody (CL488-14060) at dilution of 1:200.

  • IF Staining of mouse brain using CL488-14060

    IF Staining of mouse brain using CL488-14060

    Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using CoraLite® Plus 488 PARK2/Parkin antibody (CL488-14060) at dilution of 1:200.

  • IF Staining of mouse brain using CL488-14060

    IF Staining of mouse brain using CL488-14060

    Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using CoraLite® Plus 488 PARK2/Parkin antibody (CL488-14060) at dilution of 1:200.

Tested Applications

Positive IF detected inmouse heart tissue, mouse brain tissue
Planning an IHC experiment? We recommend our IHCeasy PARK2 Ready-To-Use IHC Kit. PARK2 primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 14060-1-AP

Recommended dilution

ApplicationDilution
Immunofluorescence (IF)IF : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

CL488-14060 targets PARK2/Parkin in IF applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen PARK2/Parkin fusion protein Ag5092 相同性解析による交差性が予測される生物種
Full Name Parkinson disease (autosomal recessive, juvenile) 2, parkin
Calculated molecular weight 52 kDa
Observed molecular weight 42-52 kDa
GenBank accession numberBC022014
Gene symbol PARK2
Gene ID (NCBI) 5071
RRIDAB_2919085
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission maxima wavelengths493 nm / 522 nm
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Parkin, a RING-type E3 ubiquitin-protein ligase, is involved in the ubiquitination pathway and contributes to protection from neurotoxicity induced by unfolded protein stresses. Its ubiquitin-protein ligase activity promotes the degradation of a variety of proteins including itself. Mutations in Parkin are implicated in the pathogenesis of autosomal recessive familial Parkinson's disease. It has 8 isoforms produced by alternative splicing.

Protocols

Product Specific Protocols
IF protocol for CL Plus 488 PARK2/Parkin antibody CL488-14060Download protocol
Standard Protocols
Click here to view our Standard Protocols