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Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
87648-2-PBS targets Phospho-PAK4 (Ser474)/PAK5 (Ser602)/PAK6 (Ser560) in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
Peptide 相同性解析による交差性が予測される生物種 |
| Full Name | p21 protein (Cdc42/Rac)-activated kinase 4 |
| Calculated molecular weight | 64 kDa |
| Observed molecular weight | 72 kDa |
| GenBank accession number | NM_001014831 |
| Gene Symbol | PAK4 |
| Gene ID (NCBI) | 10298 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | O96013 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
PAK4(p21-activated kinase 4) is also named as KIAA1142. It belongs to the protein kinase superfamily. Phospho-PAK4 (Ser474)/PAK5 (Ser602)/PAK6 (Ser560) refers to the phosphorylated forms of the Group II p21-Activated Kinases (PAKs) at specific serine residues in their kinase activation loops. These phosphorylation events are essential for the catalytic activation of Group II PAKs and serve as definitive markers of their enzymatic activity. (PMID: 17292838)