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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

CoraLite® Plus 488-conjugated Neuropeptide Y Polyclonal antibody

Neuropeptide Y Polyclonal Antibody for IF

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IF

Conjugate

CoraLite® Plus 488 Fluorescent Dye

Cat no : CL488-12833

Synonyms

CPON, Neuropeptide tyrosine, neuropeptide Y, NPY, PYY4

Validation Data Gallery

Applications:
  • IF Staining of mouse eye using CL488-12833

    IF Staining of mouse eye using CL488-12833

    Immunofluorescent analysis of (4% PFA) fixed mouse eye tissue using CoraLite® Plus 488 Neuropeptide Y antibody (CL488-12833) at dilution of 1:200.

Tested Applications

Positive IF detected inmouse eye tissue
For other applications, we recommend the unconjugated version of this antibody, 12833-1-AP

Recommended dilution

ApplicationDilution
Immunofluorescence (IF)IF : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

CL488-12833 targets Neuropeptide Y in IF applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Neuropeptide Y fusion protein Ag3568 相同性解析による交差性が予測される生物種
Full Name neuropeptide Y
Calculated molecular weight 97 aa, 11 kDa
GenBank accession numberBC029497
Gene symbol NPY
Gene ID (NCBI) 4852
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission maxima wavelengths493 nm / 522 nm
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Neuropeptide Y (NPY) is one of the most abundant peptides in the mammalian central nervous system (CNS). NPY has been linked to several physiological and pathological functions, such as feeding behaviour, memory processing, pain, anxiety, cell proliferation and many other processes in the central and peripheral nervous systems. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. In addition, NPY was suggested as a potential neuroprotective agent in Alzheimer's disease by counteracting the toxic effect of β-amyloid in an in vitro model.

Protocols

Product Specific Protocols
IF protocol for CL Plus 488 Neuropeptide Y antibody CL488-12833Download protocol
Standard Protocols
Click here to view our Standard Protocols