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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

CoraLite® Plus 488-conjugated EXOC3L2 Monoclonal antibody

EXOC3L2 Monoclonal Antibody for IF

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

IF

Conjugate

CoraLite® Plus 488 Fluorescent Dye

CloneNo.

3C1C2

Cat no : CL488-66537

Synonyms

EXOC3L2, FLJ36147, XTP7

Validation Data Gallery

Applications:
  • IF Staining of HUVEC using CL488-66537

    IF Staining of HUVEC using CL488-66537

    Immunofluorescent analysis of (-20°C Methanol) fixed HUVEC cells using CoraLite® Plus 488 EXOC3L2 antibody (CL488-66537, Clone: 3C1C2 ) at dilution of 1:200.

Tested Applications

Positive IF detected inHUVEC cells
For other applications, we recommend the unconjugated version of this antibody, 66537-1-Ig

Recommended dilution

ApplicationDilution
Immunofluorescence (IF)IF : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

CL488-66537 targets EXOC3L2 in IF applications and shows reactivity with Human samples.

Tested Reactivity Human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen EXOC3L2 fusion protein Ag26912 相同性解析による交差性が予測される生物種
Full Name exocyst complex component 3-like 2
Calculated molecular weight 46 kDa
Observed molecular weight 46 kDa
GenBank accession numberBC104947
Gene symbol EXOC3L2
Gene ID (NCBI) 90332
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission maxima wavelengths493 nm / 522 nm
Form Liquid
Purification Method Protein G purification
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

The exocyst is a protein complex that ensures spatial targeting of exocytotic vesicles to the plasma membrane. Exocyst complex component 3-like 2 (EXOC3L2) associates with the exocyst complex and mediates directional migration of endothelial cells (PMID: 21566143). The gene of human EXOC3L2 maps to chromosome 19q13.32 and encodes a deduced 409-amino acid protein with a calculated molecular mass of about 46 kDa. Mouse Exoc3l2 gene encodes an approximately 250-amino acid protein that lacks the N-terminal domain of human EXOC3L2. Mutations in EXOC3L2 gene may be associated with Alzheimer's disease.

Protocols

Product Specific Protocols
IF protocol for CL Plus 488 EXOC3L2 antibody CL488-66537Download protocol
Standard Protocols
Click here to view our Standard Protocols