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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

CoraLite®594-conjugated CMPK1 Monoclonal antibody

CMPK1 Monoclonal Antibody for IF

Host / Isotype

Mouse / IgG2b

Reactivity

Human

Applications

IF

Conjugate

CoraLite®594 Fluorescent Dye

CloneNo.

2D11G7

Cat no : CL594-67519

Synonyms

CMK, CMPK, CMPK1, Cytidine monophosphate kinase, Cytidylate kinase, Deoxycytidylate kinase, UCK, UMK, UMP CMP kinase, UMP CMPK, UMP/CMP kinase, UMP/CMPK, UMPK, Uridine monophosphate kinase

Validation Data Gallery

Applications:
  • IF Staining of HeLa using CL594-67519

    IF Staining of HeLa using CL594-67519

    Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using CoraLite®594 CMPK1 antibody (CL594-67519, Clone: 2D11G7 ) at dilution of 1:200, CL488-Phalloidin (green).

Tested Applications

Positive IF detected inHeLa cells
Planning an IHC experiment? We recommend our IHCeasy CMPK1 Ready-To-Use IHC Kit. CMPK1 primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 67519-1-Ig

Recommended dilution

ApplicationDilution
Immunofluorescence (IF)IF : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

CL594-67519 targets CMPK1 in IF applications and shows reactivity with Human samples.

Tested Reactivity Human
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Immunogen CMPK1 fusion protein Ag30084 相同性解析による交差性が予測される生物種
Full Name cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
Calculated molecular weight 228 aa, 26 kDa
Observed molecular weight 22-26 kDa
GenBank accession numberBC014961
Gene symbol CMPK1
Gene ID (NCBI) 51727
RRIDAB_2920148
Conjugate CoraLite®594 Fluorescent Dye
Excitation/Emission maxima wavelengths588 nm / 604 nm
Form Liquid
Purification Method Protein A purification
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Pyrimidine nucleoside monophosphate kinase [UMP/CMP kinase (UMP/CMPK)] (CMPK1) is also named as CMK, CMPK, UCK, UMK, UMPK and belongs to the adenylate kinase family. It plays a crucial role in the formation of UDP, CDP, and dCDP, which are required for cellular nucleic acid synthesis(PMID:11912132). CMPK1 can use a broad spectrum of phosphate donors but the best phosphate donors are ATP and dATP. CMPK1 has been reported as a prognostic marker for non-small cell lung cancer, pancreatic cancer and breast cancer (PMID: 21642870, 22838950, 27558661). The longest deduced protein contains 228 amino acids and has a calculated molecular mass of 26 kD. However, translation likely begins at the second initiation methionine, resulting in a protein of 196 amino acids(PMID:10462544). The shorter form is the endogenously translated protein(PMID:11912132). CMPK1 has 3 isoforms with the molecular mass of 22, 16 and 26 kDa.

Protocols

Product Specific Protocols
IF protocol for CL594 CMPK1 antibody CL594-67519Download protocol
Standard Protocols
Click here to view our Standard Protocols