Validation Data Gallery
Product Information
bfgfCys1 is an unconjugated recombinant anti FGF-basic (FGF2) Nanobody (VHH). Suitable for for cysteine conjugation with thiol-reactive reagents, e.g. maleimides. Note: unconjugated VHHs are not suited for usage without prior labeling, since they contain reactive Cysteines. Shipment and storage buffers contain TCEP to keep Cysteines reduced.
| Applications | Conjugation |
| Reactivity | Human |
| Conjugate | Unconjugated |
| Type | Nanobody |
| Class | Recombinant |
| Host | Alpaca |
| Affinity | 4 nM |
| Molecular Weight | 14.5 kDa |
| Form | Liquid |
| RRID | AB_3665410 |
| Storage Buffer | 10 mM HEPES pH 7.0, 500 mM NaCl, 0.09% sodium azide |
| Storage Condition | Store at -20°C |
| Shipping | dry ice |
| Background | Basic Fibroblast growth factor (FGFbasic), also known as bFGF, FGF2, FGF-β or HBGF-2, belongs to the FGF family. FGFbasic is involved in a number of biological processes including embryonic development and differentiation, neuron differentiation, survival, and regeneration, and the proliferation of cells of mesodermal origin and many cells of neuroectodermal, ectodermal, and endodermal origin (PMID 3272178, 3316527). FGFbasic is critical for human embryonic stem cells to remain in an undifferentiated state during cell culture (PMID 15782187). |
Documentation
| SDS |
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| bfgfCys1_SDS_anti-FGF-Basic recombinant VHH (EN) |