Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
28156-1-PBS targets WNT3 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.
Tested Reactivity | human, mouse |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | WNT3 fusion protein Ag27965 相同性解析による交差性が予測される生物種 |
Full Name | wingless-type MMTV integration site family, member 3 |
Calculated molecular weight | 355 aa, 40 kDa |
Observed molecular weight | 40-45 kDa |
GenBank accession number | BC114219 |
Gene Symbol | WNT3 |
Gene ID (NCBI) | 7473 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | P56703 |
Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
Storage Conditions | Store at -80°C. |
Background Information
WNT3 is also named as INT4. WNT3 is required for normal gastrulation, formation of the primitive streak, and for the formation of the mesoderm during early embryogenesis (PMID: 14872406). Wnt3 is up-regulated in cancer tissues, such as gastric cancer and lung cancer. Wnt3, as a member of Wnt family, has been proved to promote the stabilization of β-catenin to regulate the radiation sensitivity of cancer cells (PMID: 31851619).