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Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using UNC13B Polyclonal antibody (21839-1-AP)

    WB analysis using 21839-1-AP (same clone as 21839-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 21839-1-AP (UNC13B antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21839-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using UNC13B Polyclonal antibody (21839-1-AP)

    WB analysis using 21839-1-AP (same clone as 21839-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 21839-1-AP (UNC13B antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21839-1-PBS in a different storage buffer formulation.

UNC13B Polyclonal antibody, PBS Only

UNC13B Polyclonal Antibody for WB, Indirect ELISA
Cat No. 21839-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Synonyms

unc-13 homolog B , Protein unc-13 homolog B, Munc13-2

Formulation:  PBS Only
PBS, Azide, Glycerol
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

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テクニカルサポートまたはご購入後1年間の交換／補填対応を承ります。詳細はこちらをご覧ください。

Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

21839-1-PBS targets UNC13B in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen

CatNo: Ag16478

Product name: Recombinant human UNC13B protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-330 aa of BC111781

Sequence: MSLLCVRVKRAKFQGSPDKFNTYVTLKVQNVKSTTVAVRGDQPSWEQDFMFEISRLDLGLSVEVWNKGLIWDTMVGTVWIALKTIRQSDEEGPGEWSTLEAETLMKDDEICGTRNPTPHKILLDTRFELPFDIPEEEARYWTYKWEQINALGADNEYSSQEESQRKPLPTAAAQCSFEDPDSAVDDRDSDYRSETSNSFPPPYHTASQPNASVHQFPVPVRSPQQLLLQGSSRDSCNDSMQSYDLDYPERRAISPTSSSRYGSSCNVSQGSSQLSELDQYHEQDDDHRETDSIHSCHSSHSLSRDGQAGFGEQEKPLEVTGQAEKEAACE

相同性解析による交差性が予測される生物種
Full Name unc-13 homolog B (C. elegans)
Calculated molecular weight 1610 aa, 183 kDa
Observed molecular weight180 kDa
GenBank accession numberBC111781
Gene Symbol UNC13B
Gene ID (NCBI) 10497
RRIDAB_3669376
Conjugate Unconjugated
Form
FormLiquid
Purification MethodAntigen affinity purification
UNIPROT IDO14795
Storage Buffer PBS only{{ptg:BufferTemp}}7.3
Storage ConditionsStore at -80°C.

Background Information

UNC13A is a member of the unliganded-13 (UNC13) family and plays a crucial role in synaptic vesicle priming and exocytosis. UNC13B has been implicated in autism spectrum disorder (ASD), partial epilepsy, and schizophrenia (PMID: 38188011).

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