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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

CoraLite® Plus 488-conjugated TAOK3 Monoclonal antibody

TAOK3 Monoclonal Antibody for IF

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

IF

Conjugate

CoraLite® Plus 488 Fluorescent Dye

CloneNo.

1A5A9

Cat no : CL488-67451

Synonyms

DKFZp666H245, DPK, FLJ31808, hKFC A, JIK, JNK/SAPK inhibitory kinase, Jun kinase inhibitory kinase, KDS, Kinase from chicken homolog A, MAP3K18, TAO kinase 3, TAOK3

Validation Data Gallery

Applications:
  • IF Staining of human prostate cancer using CL488-67451

    IF Staining of human prostate cancer using CL488-67451

    Immunofluorescent analysis of (4% PFA) fixed human prostate cancer tissue using CoraLite® Plus 488 TAOK3 antibody (CL488-67451, Clone: 1A5A9 ) at dilution of 1:200.

  • IF Staining of human prostate cancer using CL488-67451

    IF Staining of human prostate cancer using CL488-67451

    Immunofluorescent analysis of (4% PFA) fixed human prostate cancer tissue using CoraLite® Plus 488 TAOK3 antibody (CL488-67451, Clone: 1A5A9 ) at dilution of 1:200.

Tested Applications

Positive IF detected inhuman prostate cancer tissue
For other applications, we recommend the unconjugated version of this antibody, 67451-1-Ig

Recommended dilution

ApplicationDilution
Immunofluorescence (IF)IF : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

CL488-67451 targets TAOK3 in IF applications and shows reactivity with Human samples.

Tested Reactivity Human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen TAOK3 fusion protein Ag29146 相同性解析による交差性が予測される生物種
Full Name TAO kinase 3
Calculated molecular weight 105 kDa
Observed molecular weight 100-105 kDa
GenBank accession numberBC002756
Gene symbol TAOK3
Gene ID (NCBI) 51347
RRIDAB_2919477
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission maxima wavelengths493 nm / 522 nm
Form Liquid
Purification Method Protein G purification
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Aliquoting is unnecessary for -20oC storage.

Background Information

TAOK3(Serine/threonine-protein kinase TAO3) is also named as DPK, JIK, KDS, MAP3K18 and belongs to the STE Ser/Thr protein kinase family. It acts as an activator of the p38/MAPK14 stress-activated MAPK cascade. In response to DNA damage, it is involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. And this protein can be autophosphorylated(PMID:20949042).

Protocols

Product Specific Protocols
IF protocol for CL Plus 488 TAOK3 antibody CL488-67451Download protocol
Standard Protocols
Click here to view our Standard Protocols