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  • Featured Product
  • KD/KO Validated

CoraLite® Plus 488-conjugated STOML2 Polyclonal antibody

STOML2 Polyclonal Antibody for IF

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IF

Conjugate

CoraLite® Plus 488 Fluorescent Dye

Cat no : CL488-10348

Synonyms

EPB72 like protein 2, HSPC108, SLP 2, SLP2, stomatin (EPB72) like 2, Stomatin like protein 2, STOML2

Validation Data Gallery

Applications:
  • IF Staining of HeLa using CL488-10348

    IF Staining of HeLa using CL488-10348

    Immunofluorescent analysis of (4% PFA) fixed HeLa cells using CoraLite® Plus 488 STOML2 antibody (CL488-10348) at dilution of 1:200.

Tested Applications

Positive IF detected inHeLa cells
For other applications, we recommend the unconjugated version of this antibody, 10348-1-AP

Recommended dilution

ApplicationDilution
Immunofluorescence (IF)IF : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

CL488-10348 targets STOML2 in IF applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen STOML2 fusion protein Ag0363 相同性解析による交差性が予測される生物種
Full Name stomatin (EPB72)-like 2
Calculated molecular weight 356 aa, 39 kDa
Observed molecular weight 39 kDa
GenBank accession numberBC002442
Gene symbol STOML2
Gene ID (NCBI) 30968
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission maxima wavelengths493 nm / 522 nm
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

STOML2 (Stomatin-like protein 2; also known as SLP-2) is a widely expressed mitochondrial member of the highly conserved family of stomatin proteins. STOML2 is localized mostly in mitochondrial inner membrane, minor in plasma membrane. Human STOML2 interacts with prohibitins and regulates mitochondrial biogenesis and function (21746876). In addition, plenty of studies revealed that STOML2 was overexpressed in many human cancer tissues, and its expression may be a new valuable prognostic biomarker (19839737, 21960069). Recently STOML2 has been identified as a serological biomarker for early colorectal cancer (CRC) diagnosis (21209152). Two isoforms of STOML2 exist due to the alternative splicing, with MW of 39 kDa and 33 kDa, respectively.

Protocols

Product Specific Protocols
IF protocol for CL Plus 488 STOML2 antibody CL488-10348Download protocol
Standard Protocols
Click here to view our Standard Protocols