Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
30497-1-PBS targets SLX4IP in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag33034 Product name: Recombinant human SLX4IP protein Source: e coli.-derived, PGEX-4T Tag: GST Sequence: KLRRNALKEIVKRTETKSSVTSKSQTRRDTVETSSDSVIAEIARRRNDGQASSSPPSESMGQAKDSIKAAESHWGLPVQKLEKVNQTQPEDTSGQQKPHPGERLKTGLLSRSPVCSCESASPCPKQSPRVAKTQQKRRNCSSAEDFDHHGRVSLGSDRLVPREIIVEKSKAVRVLPASELSDPGLLLKQDLAKTTSKEELHVLESLSSRHLMKNNPGQAQQTGLATNTERLSTIQNSPTKKRKKYERGH 相同性解析による交差性が予測される生物種 |
| Full Name | chromosome 20 open reading frame 94 |
| Calculated molecular weight | 46 kDa |
| Observed molecular weight | 42 kDa |
| Gene Symbol | C20orf94 |
| Gene ID (NCBI) | 128710 |
| RRID | AB_3742346 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q5VYV7 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
SLX4IP is a nuclear adaptor protein that associates with the SLX4 DNA repair scaffold, contributing to DNA damage repair, replication stress responses, and telomere maintenance. By regulating nuclease-containing repair complexes and potentially supporting ALT-mediated telomere elongation, SLX4IP plays an important role in maintaining genomic stability. Dysregulation of SLX4IP has been implicated in cancer biology, particularly in tumors utilizing alternative telomere maintenance pathways.