Validation Data Gallery
Tested Applications
| Positive WB detected in | HEK-293 cells, HEK-293, LNCaP, MG-63, U2OS cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:5000-1:50000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
30497-1-AP targets SLX4IP in WB, ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag33034 Product name: Recombinant human SLX4IP protein Source: e coli.-derived, PGEX-4T Tag: GST Sequence: KLRRNALKEIVKRTETKSSVTSKSQTRRDTVETSSDSVIAEIARRRNDGQASSSPPSESMGQAKDSIKAAESHWGLPVQKLEKVNQTQPEDTSGQQKPHPGERLKTGLLSRSPVCSCESASPCPKQSPRVAKTQQKRRNCSSAEDFDHHGRVSLGSDRLVPREIIVEKSKAVRVLPASELSDPGLLLKQDLAKTTSKEELHVLESLSSRHLMKNNPGQAQQTGLATNTERLSTIQNSPTKKRKKYERGH 相同性解析による交差性が予測される生物種 |
| Full Name | chromosome 20 open reading frame 94 |
| Calculated molecular weight | 46 kDa |
| Observed molecular weight | 42 kDa |
| Gene Symbol | C20orf94 |
| Gene ID (NCBI) | 128710 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q5VYV7 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
SLX4IP is a nuclear adaptor protein that associates with the SLX4 DNA repair scaffold, contributing to DNA damage repair, replication stress responses, and telomere maintenance. By regulating nuclease-containing repair complexes and potentially supporting ALT-mediated telomere elongation, SLX4IP plays an important role in maintaining genomic stability. Dysregulation of SLX4IP has been implicated in cancer biology, particularly in tumors utilizing alternative telomere maintenance pathways.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for SLX4IP antibody 30497-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |