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Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
87168-2-PBS targets Phospho-VASP (Ser157) in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
Peptide 相同性解析による交差性が予測される生物種 |
| Full Name | vasodilator-stimulated phosphoprotein |
| Calculated molecular weight | 380 aa, 40 kDa |
| Observed molecular weight | 50 kDa |
| GenBank accession number | BC038224 |
| Gene Symbol | VASP |
| Gene ID (NCBI) | 7408 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P50552 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
VASP belongs to the Ena/VASP family. Phospho-VASP (Ser157) is an important post-translational modification of the vasodilator-stimulated phosphoprotein (VASP). Phosphorylation at Serine 157 (Ser157) is catalyzed by protein kinase C (PKC) and Rho kinase in response to thrombin or phorbol ester stimulation in human platelets. This modification negatively regulates platelet adhesion and secretion, and serves as a key signaling event in modulating cytoskeletal dynamics and cell motility. (PMID: 16197368)