Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
87513-1-PBS targets Phospho-Filamin A (Ser2152) in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
Peptide 相同性解析による交差性が予測される生物種 |
| Full Name | filamin A, alpha (actin binding protein 280) |
| Calculated molecular weight | 2647 aa, 280 kDa |
| Observed molecular weight | 280 kDa |
| GenBank accession number | NM_001110556 |
| Gene Symbol | FLNA |
| Gene ID (NCBI) | 2316 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P21333 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
FLNA encodes a 280 kDa widely expressed actin binding protein called filamin A which can crosslinks actin filaments and links actin filaments to membrane glycoproteins to form a three-dimensional network. Phospho-Filamin A (Ser2152) is a phosphorylated form of Filamin A (FLNA), which is a large actin-binding protein that plays a crucial role in organizing the cytoskeleton and transducing signals from cell membrane to the cytoskeleton. This phosphorylation event is associated with various cellular functions, including cytoskeletal remodeling, cell migration, and focal adhesion formation. (PMID:29931263)