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Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using PSEN2-Specific Polyclonal antibody (16168-1-AP)

    WB analysis using 16168-1-AP (same clone as 16168-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 16168-1-AP (PSEN2-Specific antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16168-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of A549 cells using PSEN2-Specific Polyclonal antibody (16168-1-AP)

    WB analysis of A549 using 16168-1-AP (same clone as 16168-1-PBS)

    WB result of PSEN2-Specific antibody (16168-1-AP; 1:1200; incubated at room temperature for 1.5 hours) with sh-Control and sh-PSEN2-Specific transfected A549 cells. This data was developed using the same antibody clone with 16168-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human kidney tissue using PSEN2-Specific Polyclonal antibody (16168-1-AP)

    IHC staining of human kidney using 16168-1-AP (same clone as 16168-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 16168-1-AP (PSEN2-Specific Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 16168-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human kidney tissue using PSEN2-Specific Polyclonal antibody (16168-1-AP)

    IHC staining of human kidney using 16168-1-AP (same clone as 16168-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 16168-1-AP (PSEN2-Specific Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 16168-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human placenta tissue using PSEN2-Specific Polyclonal antibody (16168-1-AP)

    IHC staining of human placenta using 16168-1-AP (same clone as 16168-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 16168-1-AP (PSEN2-Specific Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 16168-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human placenta tissue using PSEN2-Specific Polyclonal antibody (16168-1-AP)

    IHC staining of human placenta using 16168-1-AP (same clone as 16168-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 16168-1-AP (PSEN2-Specific Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 16168-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse brain tissue using PSEN2-Specific Polyclonal antibody (16168-1-AP)

    IHC staining of mouse brain using 16168-1-AP (same clone as 16168-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 16168-1-AP (PSEN2-Specific antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 16168-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human breast cancer tissue using PSEN2-Specific Polyclonal antibody (16168-1-AP)

    IHC staining of human breast cancer using 16168-1-AP (same clone as 16168-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer using 16168-1-AP (PSEN2-Specific antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 16168-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human breast cancer tissue using PSEN2-Specific Polyclonal antibody (16168-1-AP)

    IHC staining of human breast cancer using 16168-1-AP (same clone as 16168-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer using 16168-1-AP (PSEN2-Specific antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 16168-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human colon tissue using PSEN2-Specific Polyclonal antibody (16168-1-AP)

    IHC staining of human colon using 16168-1-AP (same clone as 16168-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 16168-1-AP (PSEN2-Specific Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 16168-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human colon tissue using PSEN2-Specific Polyclonal antibody (16168-1-AP)

    IHC staining of human colon using 16168-1-AP (same clone as 16168-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 16168-1-AP (PSEN2-Specific Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 16168-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO Validated

PSEN2-Specific Polyclonal antibody, PBS Only

PSEN2-Specific Polyclonal Antibody for WB, IHC, ELISA
Cat No. 16168-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, ELISA

Synonyms

Formulation:  PBS Only
PBS, Azide, Glycerol
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

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Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

16168-1-PBS targets PSEN2-Specific in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen

Peptide

相同性解析による交差性が予測される生物種
Full Name presenilin 2 (Alzheimer disease 4)
Calculated molecular weight 50 kDa
Observed molecular weight55-60 kDa
GenBank accession numberNM_000447
Gene Symbol PSEN2
Gene ID (NCBI) 5664
RRIDAB_2170748
Conjugate Unconjugated
Form
FormLiquid
Purification MethodAntigen affinity purification
UNIPROT IDP49810
Storage Buffer PBS only{{ptg:BufferTemp}}7.3
Storage ConditionsStore at -80°C.

Background Information

Presenilins can regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. These transmembrane proteins are considered to be involved in early onset of Alzheimer's disease. Presenilin 2 mainly localizes in large neurons. It exists in a heterodimeric complex formed from the endoproteolytically processed amino-terminal (34 kDa) and carboxy-terminal (about 23 kDa) fragments.This antibody is specific to presenilin 2. It will not bind presenilin 1.

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