Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
17646-1-PBS targets PLA2G3 in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag11845 Product name: Recombinant human PLA2G3 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 160-509 aa of BC025316 Sequence: GVGDSAGNSSELGVFQGPDLCCREHDRCPQNISPLQYNYGIRNYRFHTISHCDCDTRFQQCLQNQHDSISDIVGVAFFNVLEIPCFVLEEQEACVAWYWWGGCRMYGTVPLARLQPRTFYNASWSSRATSPTPSSRSPAPPKPRQKQHLRKGPPHQKGSKRPSKANTTALQDPMVSPRLDVAPTGLQGPQGGLKPQGARWVCRSFRRHLDQCEHQIGPREIEFQLLNSAQEPLFHCNCTRRLARFLRLHSPPEVTNMLWELLGTTCFKLAPPLDCVEGKNCSRDPRAIRVSARHLRRLQQRRHQLQDKGTDERQPWPSEPLRGPMSFYNQCLQLTQAARRPDRQQKSWSQ 相同性解析による交差性が予測される生物種 |
| Full Name | phospholipase A2, group III |
| Calculated molecular weight | 509 aa, 57 kDa |
| Observed molecular weight | 57 kDa |
| GenBank accession number | BC025316 |
| Gene Symbol | PLA2G3 |
| Gene ID (NCBI) | 50487 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9NZ20 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
The PLA2G3 protein (full name: Phospholipase A2 Group III) is a member of the secreted phospholipase A2 (sPLA2) family. It is a calcium-dependent secretory protein whose primary biochemical function is to catalyze the hydrolysis of the sn-2 position of phospholipids, releasing arachidonic acid and lysophospholipids. It is an enzyme involved in the hydrolysis of membrane phospholipids and lipid metabolism, playing important roles in the development and progression of innate immunity, inflammatory diseases (such as asthma and psoriasis), atherosclerosis, and certain cancers (such as colorectal cancer and ovarian cancer).