Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
33450-1-PBS targets NEPRO in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag38276 Product name: Recombinant human C3orf17 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-168 aa of NM_015412.3 Sequence: MMAAVPPGLEPWNRVRIPKAGNRSAVTVQNPGAALDLCIAAVIKECHLVILSLKSQTLDAETDVLCAVLYSNHNRMGRHKPHLALKQVEQCLKRLKNMNLEGSIQDLFELFSSNENQPLTTKVCVVPSQPVVELVLMKVLGACKLLLRLLDCCCKTFLLTVKHLGLQE 相同性解析による交差性が予測される生物種 |
| Full Name | chromosome 3 open reading frame 17 |
| Calculated molecular weight | 65kDa，567aa |
| Observed molecular weight | 58 kDa |
| GenBank accession number | NM_015412.3 |
| Gene Symbol | C3orf17 |
| Gene ID (NCBI) | 25871 |
| RRID | AB_3742976 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity Purification |
| UNIPROT ID | Q6NW34 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
The NEPRO protein (full name: Nucleolus and Neural Progenitor Protein) belongs to the NEPRO family and is primarily localized in the nucleolus. Its core function is to serve as a key downstream factor of the Notch signaling pathway during cerebral cortex development, where it maintains the stemness of neural progenitor cells by inhibiting their differentiation into neurons, thereby ensuring normal development of the nervous system. Additionally, this protein also plays an indispensable role during pre-implantation embryonic development in mice (PMID: 26178919).