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CoraLite® Plus 488-conjugated Iduronate 2 sulfatase Monoclonal antibody

Iduronate 2 sulfatase Monoclonal Antibody for IF/ICC
Cat No. CL488-66112
Clone No.1A3F9

Host / Isotype

Mouse / IgG1

Reactivity

human, mouse, rat , pig

Applications

IF/ICC

IDS, iduronate 2 sulfatase, Idursulfase, MPS2, SIDS

Formulation:  PBS and Azide
PBS and Azide
Conjugate:  CoraLite® Plus 488
Size/Concentration: 

-/ -


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国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター(国内)に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。


保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Positive IF/ICC detected inHepG2 cells

Recommended dilution

ApplicationDilution
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

CL488-66112 targets Iduronate 2 sulfatase in IF/ICC applications and shows reactivity with human, mouse, rat , pig samples.

Tested Reactivity human, mouse, rat , pig
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen Iduronate 2 sulfatase fusion protein Ag19095 相同性解析による交差性が予測される生物種
Full Name iduronate 2-sulfatase
Calculated molecular weight312aa,35 kDa; 550aa,62 kDa
Observed molecular weight 76 kDa, 55 kDa
GenBank accession numberBC006170
Gene Symbol IDS
Gene ID (NCBI) 3423
RRIDAB_3084207
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission maxima wavelengths493 nm / 522 nm
Form Liquid
Purification MethodProtein G purification
UNIPROT IDP22304
Storage Buffer PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Iduronate 2-sulfatase (IDS) is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations causing IDS deficiency in humans result in the lysosomal storage of these glycosaminoglycans and Hunter syndrome, an X chromosome-linked disease. IDS is synthesized as two precursor forms of 76 and 90 kDa that are converted, through a 62 kDa intermediate, to 55 and 45 kDa mature polypeptides due to an internal proteolytic cleavage (PMID: 10838181).

Protocols

Product Specific Protocols
IF protocol for CL Plus 488 Iduronate 2 sulfatase antibody CL488-66112Download protocol
Standard Protocols
Click here to view our Standard Protocols
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