Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
16667-1-PBS targets IYD in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag10146 Product name: Recombinant human IYD protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 33-289 aa of BC056253 Sequence: EPRTRAEARPWVDEDLKDSSDLHQAEEDADEWQESEENVEHIPFSHNHYPEKEMVKRSQEFYELLNKRRSVRFISNEQVPMEVIDNVIRTAGTAPSGAHTEPWTFVVVKDPDVKHKIRKIIEEEEEINYMKRMGHRWVTDLKKLRTNWIKEYLDTAPILILIFKQVHGFAANGKKKVHYYNEISVSIACGILLAALQNAGLVTVTTTPLNCGPRLRVLLGRPAHEKLPMLLPVGYPSKEATVPDLKRKPLDQIMVTV 相同性解析による交差性が予測される生物種 |
| Full Name | iodotyrosine deiodinase |
| Calculated molecular weight | 289 aa, 33 kDa |
| Observed molecular weight | 33 kDa |
| GenBank accession number | BC056253 |
| Gene Symbol | IYD |
| Gene ID (NCBI) | 389434 |
| RRID | AB_1851260 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q6PHW0 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
IYD(Iodotyrosine dehalogenase 1) is also named as C6orf71, DEHAL1 and belongs to the nitroreductase family. It is a transmembrane protein that deiodinates mono-and di-iodotyrosines (MIT, DIT) and recycles iodine, a scarce element in the environment, for the efficient synthesis of thyroid hormone. This protein has 6 isoforms produced by alternative splicing.