Validation Data Gallery
Tested Applications
| Positive WB detected in | human liver tissue |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| WB | See 2 publications below |
| IHC | See 1 publications below |
| IF | See 1 publications below |
Product Information
16667-1-AP targets IYD in WB, IF, IHC, ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Cited Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag10146 Product name: Recombinant human IYD protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 33-289 aa of BC056253 Sequence: EPRTRAEARPWVDEDLKDSSDLHQAEEDADEWQESEENVEHIPFSHNHYPEKEMVKRSQEFYELLNKRRSVRFISNEQVPMEVIDNVIRTAGTAPSGAHTEPWTFVVVKDPDVKHKIRKIIEEEEEINYMKRMGHRWVTDLKKLRTNWIKEYLDTAPILILIFKQVHGFAANGKKKVHYYNEISVSIACGILLAALQNAGLVTVTTTPLNCGPRLRVLLGRPAHEKLPMLLPVGYPSKEATVPDLKRKPLDQIMVTV 相同性解析による交差性が予測される生物種 |
| Full Name | iodotyrosine deiodinase |
| Calculated molecular weight | 289 aa, 33 kDa |
| Observed molecular weight | 33 kDa |
| GenBank accession number | BC056253 |
| Gene Symbol | IYD |
| Gene ID (NCBI) | 389434 |
| RRID | AB_1851260 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q6PHW0 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
IYD(Iodotyrosine dehalogenase 1) is also named as C6orf71, DEHAL1 and belongs to the nitroreductase family. It is a transmembrane protein that deiodinates mono-and di-iodotyrosines (MIT, DIT) and recycles iodine, a scarce element in the environment, for the efficient synthesis of thyroid hormone. This protein has 6 isoforms produced by alternative splicing.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for IYD antibody 16667-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
Toxicology Structure-activity relationships of 44 halogenated compounds for iodotyrosine deiodinase-inhibitory activity. | ||
Cells Agonist Antibody Converts Stem Cells into Migrating Brown Adipocyte-Like Cells in Heart. | ||
Breast Cancer Res Treat LncRNA HOTAIR as a ceRNA is related to breast cancer risk and prognosis | ||
Cell Tissue Res The role of vitamin D receptor in predentin mineralization and dental repair after injury |
