Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
33149-1-PBS targets EPS8L1 in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag38144 Product name: Recombinant human EPS8L1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 247-596 aa of BC015763 Sequence: LTSDAVALLRDNVTPRENELWTSLGDSWTRPGLELSPEEGPPYRPEFFSGWEPPVTDPQSRAWEDPVEKQLQHERRRRQQSAPQVAVNGHRDLEPESEPQLESETAGKWVLCNYDFQARNSSELSVKQRDVLEVLDDSRKWWKVRDPAGQEGYVPYNILTPYPGPRLHHSQSPARSLNSTPPPPPAPAPAPPPALARPRWDRPRWDSCDSLNGLDPSEKEKFSQMLIVNEELQARLAQGRSGPSRAVPGPRAPEPQLSPGSDASEVRAWLQAKGFSSGTVDALGVLTGAQLFSLQKEELRAVSPEEGARVYSQVTVQRSLLEDKEKVSELEAVMEKQKKKVEGEVEMEVI 相同性解析による交差性が予測される生物種 |
| Full Name | EPS8-like 1 |
| Calculated molecular weight | 80 kDa |
| Observed molecular weight | 80-85 kDa |
| GenBank accession number | BC015763 |
| Gene Symbol | EPS8L1 |
| Gene ID (NCBI) | 54869 |
| RRID | AB_3742872 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity Purification |
| UNIPROT ID | Q8TE68 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
EPS8L1 encodes Epidermal Growth Factor Receptor Kinase Substrate 8-like Protein 1, a protein related to EPS8 and positioned within the EPS8 signaling adaptor family. Its biology is centered on signaling at the cell cortex, where it is connected to ruffle membrane and cytosolic compartments and is associated with positive regulation of ruffle assembly. The protein contains multiple interaction-related domains, including a PTB/PI domain, phosphotyrosine-binding domain, SH3 domain, and SAM domain, supporting a role in signal-dependent molecular interactions.