Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
87904-1-PBS targets EPHA2 as part of a matched antibody pair:
MP03249-1: 87904-2-PBS capture and 87904-1-PBS detection (validated in Cytometric bead array)
Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.
This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.
| Tested Reactivity | mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
CatNo: Eg8778 Product name: Recombinant mouse Epha2 protein Source: mammalian cells-derived, V37 Tag: C-rFc Domain: 26-538 aa of NM_010139.3 Sequence: KEVVLLDFAAMKGELGWLTHPYGKGWDLMQNIMDDMPIYMYSVCNVVSGDQDNWLRTNWVYREEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYAESDVDYGTNFQKRQFTKIDTIAPDEITVSSDFEARNVKLNVEERMVGPLTRKGFYLAFQDIGACVALLSVRVYYKKCPEMLQSLARFPETIAVAVSDTQPLATVAGTCVDHAVVPYGGEGPLMHCTVDGEWLVPIGQCLCQEGYEKVEDACRACSPGFFKSEASESPCLECPEHTLPSTEGATSCQCEEGYFRAPEDPLSMSCTRPPSAPNYLTAIGMGAKVELRWTAPKDTGGRQDIVYSVTCEQCWPESGECGPCEASVRYSEPPHALTRTSVTVSDLEPHMNYTFAVEARNGVSGLVTSRSFRTASVSINQTEPPKVRLEDRSTTSLSVTWSIPVSQQSRVWKYEVTYRKKGDANSYNVRRTEGFSVTLDDLAPDTTYLVQVQALTQEGQGAGSKVHEFQTLSTEGSANMAV 相同性解析による交差性が予測される生物種 |
| Full Name | Eph receptor A2 |
| Calculated molecular weight | 109 kDa |
| Observed molecular weight | 130 kDa |
| GenBank accession number | NM_010139.3 |
| Gene Symbol | Epha2 |
| Gene ID (NCBI) | 13836 |
| RRID | AB_3745819 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | Q03145 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
EPH receptor A2 (EPHA2) is a receptor tyrosine kinase (RTK) of the Eph receptor family that primarily binds glycosylphosphatidylinositol (GPI)-anchored ephrin-A ligands, especially ephrin-A1 (EFNA1), to mediate contact-dependent cell-cell signaling. In mice, Epha2 is broadly expressed in epithelial, endothelial, and selected stromal compartments, where it regulates cell adhesion, polarity, migration, proliferation, barrier organization, and tissue architecture.