Validation Data Gallery
Tested Applications
| Positive FC detected in | HUVEC cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Flow Cytometry (FC) | FC : 5 ul per 10^6 cells in a 100 µl suspension |
| This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
CL488-FcA98325 targets EPCR/CD201 in FC applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
CatNo: Eg2339 Product name: Recombinant Human PROCR protein (rFc Tag) Source: mammalian cells-derived, pHZ-KIsec-C-rFc Tag: C-rFc Domain: 18-210 aa of BC014451 Sequence: SQDASDGLQRLHMLQISYFRDPYHVWYQGNASLGGHLTHVLEGPDTNTTIIQLQPLQEPESWARTQSGLQSYLLQFHGLVRLVHQERTLAFPLTIRCFLGCELPPEGSRAHVFFEVAVNGSSFVSFRPERALWQADTQVTSGVVTFTLQQLNAYNRTRYELREFLEDTCVQYVQKHISAENTKGSQTSRSYTS 相同性解析による交差性が予測される生物種 |
| Full Name | protein C receptor, endothelial (EPCR) |
| Calculated molecular weight | 238 aa, 27 kDa |
| GenBank accession number | BC014451 |
| Gene Symbol | PROCR |
| Gene ID (NCBI) | 10544 |
| Conjugate | CoraLite® Plus 488 Fluorescent Dye |
| Excitation/Emission maxima wavelengths | 493 nm / 522 nm |
| 激发激光 | Blue laser (488 nm) |
| Form | |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | Q9UNN8 |
| Storage Buffer | PBS with 0.09% sodium azide and 0.5% BSA{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
Background Information
EPCR (endothelial cell protein C receptor), also known as CD201, is a type 1 transmembrane protein that is primarily found on endothelial cells. It exhibits sequence and three-dimensional structural homology with the major histocompatibility class 1/CD1 family of proteins, particularly CD1d. It binds activated protein C and enhances protein C activation by the thrombin-thrombomodulin complex. It plays a role in the protein C pathway controlling blood coagulation.
Protocols
| Product Specific Protocols | |
|---|---|
| FC protocol for CL Plus 488 EPCR/CD201 antibody CL488-FcA98325 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |