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Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
86235-1-PBS targets Cytokeratin 16 in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
Peptide 相同性解析による交差性が予測される生物種 |
| Full Name | keratin 16 |
| Calculated molecular weight | 473 aa, 51 kDa |
| Observed molecular weight | 48-50 kDa |
| GenBank accession number | BC039169 |
| Gene Symbol | Cytokeratin 16 |
| Gene ID (NCBI) | 3868 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P08779 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
Cytokeratin 16 is a Type I acidic keratin (classified as KRT16 in the human gene nomenclature) that pairs with Type II basic keratins (e.g., CK-6) to form intermediate filaments in epithelial cells. It is prominently expressed in stratified epithelia, particularly under conditions of stress, proliferation, or pathology. CK-16 is constitutively expressed in specialized epithelia (e.g., nail beds, hair follicles, oral mucosa) but is normally absent in healthy, quiescent skin.