• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0
×

Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

Use Able AI chat for product recommendations

Validation Data Gallery

Filter:
  • Western Blot (WB) analysis of mouse brain tissue using CPLX2 Polyclonal antibody (18149-1-AP)

    WB analysis of mouse brain using 18149-1-AP (same clone as 18149-1-PBS)

    mouse and rat brain tissue were subjected to SDS PAGE followed by western blot with 18149-1-AP (CPLX2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18149-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of A549 cells using CPLX2 Polyclonal antibody (18149-1-AP)

    WB analysis of A549 using 18149-1-AP (same clone as 18149-1-PBS)

    WB result of CPLX2 antibody (18149-1-AP; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-CPLX2 transfected A549 cells. This data was developed using the same antibody clone with 18149-1-PBS in a different storage buffer formulation.

  • Immunoprecipitation (IP) experiment of A549 cells using CPLX2 Polyclonal antibody (18149-1-AP)

    IP experiment of A549 using 18149-1-AP (same clone as 18149-1-PBS)

    IP result of anti-CPLX2 (IP:18149-1-AP, 4ug; Detection:18149-1-AP 1:1000) with A549 cells lysate 600 ug. This data was developed using the same antibody clone with 18149-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human brain tissue using CPLX2 Polyclonal antibody (18149-1-AP)

    IHC staining of human brain using 18149-1-AP (same clone as 18149-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 18149-1-AP (CPLX2 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18149-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human brain tissue using CPLX2 Polyclonal antibody (18149-1-AP)

    IHC staining of human brain using 18149-1-AP (same clone as 18149-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 18149-1-AP (CPLX2 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18149-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of A549 cells using CPLX2 Polyclonal antibody (18149-1-AP)

    IF Staining of A549 using 18149-1-AP (same clone as 18149-1-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed A549 cells using CPLX2 antibody (18149-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 18149-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO Validated

CPLX2 Polyclonal antibody, PBS Only

CPLX2 Polyclonal Antibody for WB, IHC, IF/ICC, IP, Indirect ELISA
Cat No. 18149-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, IF/ICC, IP, Indirect ELISA

Synonyms

Formulation:  PBS Only
PBS, Azide, Glycerol
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

ご購入について

国内販売は「コスモ・バイオ株式会社」を通じて行っております。お見積り・ご注文はお近くの販売代理店へご連絡ください。

国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター（国内）に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。

保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換／補填対応を承ります。詳細はこちらをご覧ください。

Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

18149-1-PBS targets CPLX2 in WB, IHC, IF/ICC, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen

CatNo: Ag12838

Product name: Recombinant human CPLX2 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-134 aa of BC093706

Sequence: MDFVMKQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTVLKYLPGPLQDMFKK

相同性解析による交差性が予測される生物種
Full Name complexin 2
Calculated molecular weight 134 aa, 15 kDa
Observed molecular weight 18-20 kDa
GenBank accession numberBC093706
Gene Symbol CPLX2
Gene ID (NCBI) 10814
RRIDAB_2276580
Conjugate Unconjugated
Form
FormLiquid
Purification MethodAntigen affinity purification
UNIPROT IDQ6PUV4
Storage Buffer PBS only{{ptg:BufferTemp}}7.3
Storage ConditionsStore at -80°C.

Background Information

Complexins are soluble proteins that regulate the activity of soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complexes necessary for vesicle fusion. Neuronal specific complexin 1 (CPLX1) has inhibitory and stimulatory effects on exocytosis by clamping trans-SNARE complexes in a prefusion state and promoting conformational changes to facilitate membrane fusion following cell stimulation. Complexin2 (CPLX2) is a pre-synaptic protein believed to regulate neurotransmitter release from pre-synaptic terminals, it is downregulated in schizophrenic patients suffering from depression, animal models of depression and neurological disorders such as Huntington's disease in which depression is a major symptom.

||
New chat

Able™

正在加载，请稍候...