Validation Data Gallery
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Tested Applications
| Positive WB detected in | VCaP cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
81847-2-RR targets AR-V7 in WB, ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
Peptide 相同性解析による交差性が予測される生物種 |
| Full Name | androgen receptor |
| Calculated molecular weight | 644aa, 67 kDa |
| Observed molecular weight | 85 kDa |
| GenBank accession number | NM_001348061 |
| Gene Symbol | AR |
| Gene ID (NCBI) | 367 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P10275 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
Androgen Receptor Splice Variant 7 (AR-V7) is a truncated, constitutively active isoform of the human androgen receptor (AR). The presence of the AR-V7 protein is highly correlated with clinical resistance to next-generation androgen receptor signaling inhibitors (ARSIs), such as enzalutamide and abiraterone.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for AR-V7 antibody 81847-2-RR | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |