Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
81847-2-PBS targets AR-V7 in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
Peptide 相同性解析による交差性が予測される生物種 |
| Full Name | androgen receptor |
| Calculated molecular weight | 644aa, 67 kDa |
| Observed molecular weight | 85 kDa |
| GenBank accession number | NM_001348061 |
| Gene Symbol | AR |
| Gene ID (NCBI) | 367 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P10275 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
Androgen Receptor Splice Variant 7 (AR-V7) is a truncated, constitutively active isoform of the human androgen receptor (AR). The presence of the AR-V7 protein is highly correlated with clinical resistance to next-generation androgen receptor signaling inhibitors (ARSIs), such as enzalutamide and abiraterone.
