×
Use Able AI chat for product recommendations

Validation Data Gallery

Filter:
  • Western Blot (WB) analysis of fetal human brain tissue using APLP1 Recombinant monoclonal antibody (87113-1-RR)

    WB analysis of fetal human brain using 87113-1-RR (same clone as 87113-1-PBS)

    fetal human brain tissue were subjected to SDS PAGE followed by western blot with 87113-1-RR (APLP1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 87113-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of mouse brain tissue using APLP1 Recombinant monoclonal antibody (87113-1-RR)

    WB analysis of mouse brain using 87113-1-RR (same clone as 87113-1-PBS)

    mouse brain tissue were subjected to SDS PAGE followed by western blot with 87113-1-RR (APLP1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 87113-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse brain tissue using APLP1 Recombinant monoclonal antibody (87113-1-RR)

    IHC staining of mouse brain using 87113-1-RR (same clone as 87113-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 87113-1-RR (APLP1 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 87113-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse brain tissue using APLP1 Recombinant monoclonal antibody (87113-1-RR)

    IHC staining of mouse brain using 87113-1-RR (same clone as 87113-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 87113-1-RR (APLP1 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 87113-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of mouse brain tissue using APLP1 Recombinant monoclonal antibody (87113-1-RR)

    IF Staining of mouse brain using 87113-1-RR (same clone as 87113-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse brain tissue using APLP1 antibody (87113-1-RR, Clone: 252210C4 ) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 87113-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 87113-1-RR

    Affinity and Kinetic Characterization of 87113-1-RR

    Biolayer interferometry (BLl) kinetic assays of 87113-1-RR against Human APLP1 were performed. The affinity constant is below 1 pM.

APLP1 Recombinant monoclonal antibody, PBS Only

APLP1 Uni-rAb® Recombinant Antibody for WB, IHC, IF-P, Indirect ELISA
Cat No. 87113-1-PBS
Clone No.252210C4

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, IF-P, Indirect ELISA

Synonyms

A4, Amyloid beta, Amyloid beta precursor like protein 1, Amyloid like protein 1, Amyloid-like protein 1

Formulation:  PBS Only
PBS, Azide, Glycerol
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

ご購入について

国内販売は「コスモ・バイオ株式会社」を通じて行っております。お見積り・ご注文はお近くの販売代理店へご連絡ください。

国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター（国内）に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。

保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換／補填対応を承ります。詳細はこちらをご覧ください。

Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

87113-1-PBS targets APLP1 in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen

CatNo: Eg5634

Product name: Recombinant Human APLP1 protein (rFc Tag)

Source: mammalian cells-derived, V37

Tag: C-rFc

Domain: 39-580 aa of NM_005166.4

Sequence: SLAGGSPGAAEAPGSAQVAGLCGRLTLHRDLRTGRWEPDPQRSRRCLRDPQRVLEYCRQMYPELQIARVEQATQAIPMERWCGGSRSGSCAHPHHQVVPFRCLPGEFVSEALLVPEGCRFLHQERMDQCESSTRRHQEAQEACSSQGLILHGSGMLLPCGSDRFRGVEYVCCPPPGTPDPSGTAVGDPSTRSWPPGSRVEGAEDEEEEESFPQPVDDYFVEPPQAEEEEETVPPPSSHTLAVVGKVTPTPRPTDGVDIYFGMPGEISEHEGFLRAKMDLEERRMRQINEVMREWAMADNQSKNLPKADRQALNEHFQSILQTLEEQVSGERQRLVETHATRVIALINDQRRAALEGFLAALQADPPQAERVLLALRRYLRAEQKEQRHTLRHYQHVAAVDPEKAQQMRFQVHTHLQVIEERVNQSLGLLDQNPHLAQELRPQIQELLHSEHLGPSELEAPAPGGSSEDKGGLQPPDSKDDTPMTLPKGSTEQDAASPEKEKMNPLEQYERKVNASVPRGFPFHSSEIQRDELAPAGTGVSRE

相同性解析による交差性が予測される生物種
Full Name amyloid beta (A4) precursor-like protein 1
Calculated molecular weight72 kDa
Observed molecular weight80 kDa
GenBank accession numberNM_005166.4
Gene Symbol APLP1
Gene ID (NCBI) 333
RRIDAB_3745348
Conjugate Unconjugated
Form
FormLiquid
Purification MethodProtein A purification
UNIPROT IDP51693-1
Storage Buffer PBS only{{ptg:BufferTemp}}7.3
Storage ConditionsStore at -80°C.

Background Information

APLP1 (Amyloid Precursor-Like Protein 1) is a member of the amyloid precursor protein (APP) family, which also includes APP and APLP2. It is a type I transmembrane glycoprotein that is highly and predominantly expressed in the central nervous system, especially at the postsynaptic density of neurons. Functionally, APLP1 plays important roles in synaptic adhesion, synaptogenesis, and neurite outgrowth. It can form homophilic trans-interactions between neighboring cells, contributing to cell-cell adhesion and the formation of synaptic structures. Its proteolytic processing by α-, β-, and γ-secretases releases intracellular fragments that may participate in transcriptional regulation and signal transduction, potentially influencing gene expression and neuronal survival.

||
New chat

Able™

正在加载，请稍候...