• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0
×

Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

MVK Monoclonal antibody

MVK Monoclonal Antibody for WB, ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

Human

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

2F1D3

Cat no : 67820-1-Ig

Synonyms

FLJ96772, LRBP, mevalonate kinase, MK, MVK, MVLK

Validation Data Gallery

Applications:
  • WB analysis using 67820-1-Ig

    WB analysis using 67820-1-Ig

    Various lysates were subjected to SDS PAGE followed by western blot with 67820-1-Ig (MVK antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

  • WB analysis of U2OS using 67820-1-Ig

    WB analysis of U2OS using 67820-1-Ig

    U2OS cells were subjected to SDS PAGE followed by western blot with 67820-1-Ig (MVK antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

Tested Applications

Positive WB detected inLNCaP cells, U2OS cells, HepG2 cells, Jurkat cells, K-562 cells
Planning an IF experiment? We recommend our CoraLite® Plus 488 conjugated versions of this antibody.

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:5000-1:50000
Sample-dependent, check data in validation data gallery

Product Information

67820-1-Ig targets MVK in WB, ELISA applications and shows reactivity with Human samples.

Tested Reactivity Human
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Immunogen MVK fusion protein Ag28887 相同性解析による交差性が予測される生物種
Full Name mevalonate kinase
Calculated molecular weight 396 aa, 42 kDa
Observed molecular weight 42 kDa
GenBank accession numberBC016140
Gene symbol MVK
Gene ID (NCBI) 4598
RRIDAB_2918583
Conjugate Unconjugated
Form Liquid
Purification Method Protein A purification
Storage Buffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Aliquoting is unnecessary for -20oC storage.

Background Information

MVK (Mevalonate kinase) is a 42 kDa cytoplasmic protein that belongs to the GHMP kinase family. Mevalonate kinase catalyzes the ATP-dependent phosphorylation of mevalonic acid to form mevalonate 5-phosphate. Defects in mevalonate kinase can cause mevalonic aciduria (MEVA). It is an accumulation of mevalonic acid which causes a variety of symptoms such as psychomotor retardation, dysmorphic features, cataracts, hepatosplenomegaly, lymphadenopathy, anemia, hypotonia, myopathy and ataxia.

Protocols

Product Specific Protocols
WB protocol for MVK antibody 67820-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols