CoraLite® Plus 488-conjugated IFI16 Monoclonal antibody
IFI16 Monoclonal Antibody for IF
Host / Isotype
Mouse / IgG1
Reactivity
Human
Applications
IF
Conjugate
CoraLite® Plus 488 Fluorescent Dye
CloneNo.
1C10D7
Cat no : CL488-67790
Synonyms
Validation Data Gallery
Applications:
Tested Applications
| Positive IF detected in | HeLa cells |
Planning an IHC experiment? We recommend our IHCeasy IFI16 Ready-To-Use IHC Kit. IFI16 primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 67790-1-Ig
Recommended dilution
| Application | Dilution |
|---|---|
| Immunofluorescence (IF) | IF : 1:200-1:800 |
| Sample-dependent, check data in validation data gallery | |
Product Information
CL488-67790 targets IFI16 in IF applications and shows reactivity with Human samples.
| Tested Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | IFI16 fusion protein Ag30314 相同性解析による交差性が予測される生物種 |
| Full Name | interferon, gamma-inducible protein 16 |
| Calculated molecular weight | 729 aa, 82 kDa |
| Observed molecular weight | 85-95 kDa |
| GenBank accession number | BC017059 |
| Gene symbol | IFI16 |
| Gene ID (NCBI) | 3428 |
| Conjugate | CoraLite® Plus 488 Fluorescent Dye |
| Excitation/Emission maxima wavelengths | 493 nm / 522 nm |
| Form | Liquid |
| Purification Method | Protein G purification |
| Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
IFI16 is a member of a family of interferon-inducible nuclear proteins involved in transcriptional regulation functions as a transcriptional repressor. IFI16 may be involved in TP53-mediated transcriptional activation by enhancing TP53 sequence-specific DNA binding and modulating TP53 phosphorylation status. It has been reported that IFI16 participates in the regulation of autophagy, TP53-mediated cell death and innate immune response.
Protocols
| Product Specific Protocols | |
|---|---|
| IF protocol for CL Plus 488 IFI16 antibody CL488-67790 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
