Fetuin-A Recombinant antibody
Fetuin-A Recombinant Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
Human
Applications
WB
Conjugate
Unconjugated
CloneNo.
1E4
Cat no : 80793-1-RR
Synonyms
Validation Data Gallery
Tested Applications
Positive WB detected in | human plasma, human heart tissue |
Recommended dilution
Application | Dilution |
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Western Blot (WB) | WB : 1:2000-1:10000 |
Sample-dependent, check data in validation data gallery |
Product Information
80793-1-RR targets Fetuin-A in WB applications and shows reactivity with Human samples.
Tested Reactivity | Human |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | Fetuin-A fusion protein Ag9853 相同性解析による交差性が予測される生物種 |
Full Name | alpha-2-HS-glycoprotein |
Calculated molecular weight | 367 aa, 39 kDa |
Observed molecular weight | 58 kDa |
GenBank accession number | BC048198 |
Gene symbol | AHSG |
Gene ID (NCBI) | 197 |
RRID | AB_2918913 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Aliquoting is unnecessary for -20oC storage. |
Background Information
Fetuin-A, also named as Alpha2-HS glycoprotein (AHSG), is a member of cystatin superfamily of protease inhibitors. It is a highly expressed glycoprotein in various fetal tissues whereas it is mainly expressed by the liver in adults. Fetuin A, an extracellular inhibitor of transforming growth factor β, is a profibrogenic stimulus in liver disease. Circulating fetuin-A may be a beneficial serum biomarker in the detection of liver and vascular fibrosis progression in patients with non-alcoholic fatty liver disease. It is also involved in several functions, such as endocytosis, brain development and the formation of bone tissue. Fetuin-A exerts its effects on the cardiovascular system by two different mechanisms. On the one hand it inhibits ins signaling and induces ins resistance contributing to the onset of atherosclerosis and on the other hand it inhibits calcium deposition and protects from vascular calcification.
Protocols
Product Specific Protocols | |
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WB protocol for Fetuin-A antibody 80793-1-RR | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |