Endoglin/CD105 Antibody CL488-67075

適用アプリケーション

アプリケーション:

IF, FC
Application not tested? Please see our Guarantee

Endoglin/CD105 Antibody IF Human liver cancer tissue CL488-67075

Immunofluorescent analysis of (4% PFA) fixed Human liver cancer tissue using CoraLite®488 Endoglin/CD105 antibody (CL488-67075, Clone: 2D5E8 ) at dilution of 1:200.

Endoglin/CD105 Antibody FC HUVEC cells CL488-67075

1X10^6 HUVEC cells were intracellularly stained with 0.4 ug CoraLite®488 Anti-Human Endoglin/CD105 (CL488-67075, Clone:2D5E8) (red), or 0.4 ug Mouse IgG2b Isotype Control (CL488-66360-3, Clone: K11B8C4B5) (blue). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C).

種特異性:

Human

IF ポジティブ:

Human liver cancer tissue

FC ポジティブ:

HUVEC cells

推奨希釈倍率:

IF : 1:50-1:500

Excitation/Emission maxima wavelengths:

488 nm/515 nm

Protocols

Product-specific protocols

Standard Protocols

製品情報

由来:

Mouse

精製方法:

Protein A purification

アイソタイプ:

IgG2b

バッファー/保存方法:

PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. Store at -20^oC. Avoid exposure to light. Aliquoting is unnecessary for -20^oC storage.

ターゲット情報

免疫原:

Endoglin/CD105 fusion protein Ag27837

正式名:

endoglin

計算分子量:

71 kDa

検出分子量:

95-100 kDa

GenBank accession number:

BC014271

Gene ID (NCBI):

2022

遺伝子シンボル:

ENG

別名:

CD105, END, endoglin, Endoglin/CD105, ENG, FLJ41744, HHT1, ORW, ORW1

背景説明

Endoglin (ENG, CD105) is a homodimeric cell membrane glycoprotein of 180 kDa, composed of disulphide-linked subunits of 95 kDa. Endoglin is a proliferation-associated and hypoxia-inducible protein mainly expressed on vascular endothelial cells. It acts as an accessory receptor for transforming growth factor beta (TFG-β) and is involved in vascular development and remodelling. The important role of Endoglin in angiogenesis and in tumor progression makes it an ideal target for antiangiogenic therapy and a good marker for tumor prognosis. (PMID: 1326540; 14528280; 21737653; 12773481)

CoraLite®488 Endoglin/CD105 抗体 0 文献

Mouse Monoclonal| カタログ番号: CL488-67075 |クローン番号: 2D5E8

--

（希望販売価格）