Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
11356-1-PBS targets fibrosin in Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag1870 Product name: Recombinant human FBRS protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-344 aa of BC014212 Sequence: MHVRVAYMILRHQEKMKGDSHKLDFRNDLLPCLPGPYGALPPGQELSHPASLFTATGAVHAAANPFTAAPGAHGPFLSPSTHIDPFGRPTSFASLAALSNGAFGGLGSPTFNSGAVFAQKESPGAPPAFASPPDPWGRLHRSPLTFPAWVRPPEAARTPGSDKERPVERREPSITKEEKDRDLPFSRPQLRVSPATPKARAGEEGPRPTKESVRVKEERKEEAAAAAAAAAAAAAAAAAAATGPQGLHLLFERPRPPPFLGPSPPDRCAGFLEPTWLAAPPRLARPPRFYEAGEELTGPGAVAAARLYGLEPAHPLLYSRLAPPPPPAAAPGTPHLLPALMKPQ 相同性解析による交差性が予測される生物種 |
| Full Name | fibrosin |
| Calculated molecular weight | 52 kDa |
| Observed molecular weight | 48-52 kDa |
| GenBank accession number | BC014212 |
| Gene Symbol | fibrosin |
| Gene ID (NCBI) | 64319 |
| RRID | AB_10697650 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9HAH7 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
Fibrosin is a lymphokine secreted by activated lymphocytes that induces fibroblast proliferation FBRS (or FBS1) gene, encoding fibrosin (or fibrosin-1), was first cloned by Prakash et al. and was found to be able to stimulate several biological activities related to scarring as a fibrogenic lymphokine. Fibrosin is secreted by activated lymphocytes that induce fibroblast proliferation. In vitro application of fibrosin stimulates expression of alpha smooth muscle actin fibers and plays an important role in up regulating the appearance of myofibroblasts during wound healing and possibly in fibrotic diseases. Fibrosin is also implicated in alcohol-induced hepatic fibrosis in vivo.