Validation Data Gallery
| Neutralization | Measured by its ability to neutralize Human beta-NGF induced proliferation of TF-1 cell line (human erythroleukemic cell line) . The half neutralization dose (ND50) is typically 4-20 ng/mL in the presence of 2 ng/mL human beta-NGF. |
Product Information
69009-1-Ig targets NeutraKine® Beta NGF in Neutralization, ELISA, Blocking assay applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Cited Reactivity | human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen |
Product name: HumanKine® recombinant human beta NGF protein Source: -derived, Tag: Sequence: 相同性解析による交差性が予測される生物種 |
| Full Name | nerve growth factor (beta polypeptide) |
| Gene Symbol | NGF |
| Gene ID (NCBI) | 4803 |
| RRID | AB_2882927 |
| Conjugate | Unconjugated |
| Form | |
| Form | Lyophilized Powder |
| Purification Method | Protein G purification |
| UNIPROT ID | P01138 |
| Storage Buffer | Sterile PBS{{ptg:BufferTemp}}7.4 |
| Endotoxin | <0.1 EU/μg |
| Reconstitution | This product was lyophilized from a 0.2 μm filtered solution in PBS. Reconstitute at 1.0 mg/mL in sterile H2O before use. |
| Stability and Storage | Lyophilized antibodies are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products. |
Background Information
Beta nerve growth factor (NGF) is critical for the survival and maintenance of sympathetic and sensory neurons and may play an important role in the regulation of the immune system (PMID 16842161). The presence of beta NGF in immune cells, endocrine cells, and the CNS limbic areas suggests that beta NGF may function as an intracellular messenger to regulate the body's response to stress (PMID 19442684).
This antibody can be used to neutralize the bioactivity of Beta NGF.