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ZMAT3 Polyclonal antibody

ZMAT3 Polyclonal Antibody for WB, IP, ELISA
Cat No. 10504-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, IF, IP, ELISA

p53 activated gene 608 protein, PAG608, WIG 1, WIG1, Zinc finger protein WIG 1, zinc finger, matrin type 3, ZMAT3

Formulation:  PBS and Azide
PBS and Azide
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 

-/ -


ご購入について

国内販売は「コスモ・バイオ株式会社」を通じて行っております。お見積り・ご注文はお近くの販売代理店へご連絡ください。


国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター(国内)に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。


保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Positive WB detected inCOLO 320 cells, rat testis tissue, HEK-293 cells, HepG2 cells, mouse testis tissue
Positive IP detected inmouse testis tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:2000-1:16000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

10504-1-AP targets ZMAT3 in WB, IHC, IF, IP, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen ZMAT3 fusion protein Ag0780 相同性解析による交差性が予測される生物種
Full Name zinc finger, matrin type 3
Calculated molecular weight 32 kDa
Observed molecular weight 32 kDa
GenBank accession numberBC002896
Gene Symbol ZMAT3
Gene ID (NCBI) 64393
RRIDAB_2217579
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9HA38
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

ZMAT3 is a p53-induced zinc finger protein, and a role in the TP53-dependent growth regulatory pathway, contribute to TP53-mediated apoptosis by regulation of TP53 expression and translocation to the nucleus and nucleolus. Acts as a bona fide target gene of p53/TP53.

Protocols

Product Specific Protocols
WB protocol for ZMAT3 antibody 10504-1-APDownload protocol
IP protocol for ZMAT3 antibody 10504-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouse

Mol Cell

Zmat3 Is a Key Splicing Regulator in the p53 Tumor Suppression Program.

Authors - Kathryn T Bieging-Rolett
humanWB

J Cell Mol Med

Xanthatin synergizes with cisplatin to suppress homologous recombination through JAK2/STAT4/BARD1 axis in human NSCLC cells.

Authors - Jian Zhang
humanWB,IF,IP

FEBS Lett

The p53 target protein Wig-1 binds hnRNP A2/B1 and RNA Helicase A via RNA.

Authors - Prahl Magdalena M
ratWB

J Physiol Sci

Tolfenamic acid inhibits ROS-generating oxidase Nox1-regulated p53 activity in intrastriatal injection of malonic acid rats.

Authors - Xin Yang
humanIHC

Int J Gen Med

Upregulation of ZMAT3 is Associated with the Poor Prognosis of Breast Cancer

Authors - Meng Wu
humanWB

Cell Rep

The ribosomal protein L22 binds the MDM4 pre-mRNA and promotes exon skipping to activate p53 upon nucleolar stress

Authors - Jennifer Jansen
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