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CoraLite® Plus 488-conjugated XBP-1U specific Polyclonal antibody
XBP-1U specific Polyclonal Antibody for FC (Intra)
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
FC (Intra)
Conjugate
CoraLite® Plus 488 Fluorescent Dye
Cat no : CL488-25997
Synonyms
Validation Data Gallery
Tested Applications
Positive FC detected in | HepG2 cells |
Recommended dilution
Application | Dilution |
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Flow Cytometry (FC) | FC : 0.80 ug per 10^6 cells in a 100 µl suspension |
Sample-dependent, check data in validation data gallery |
Product Information
CL488-25997 targets XBP-1U specific in FC (Intra) applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | XBP-1U specific fusion protein Ag21714 相同性解析による交差性が予測される生物種 |
Full Name | X-box binding protein 1 |
Calculated molecular weight | 261 aa, 29 kDa |
Observed molecular weight | 32 kDa |
GenBank accession number | BC000938 |
Gene symbol | XBP1 |
Gene ID (NCBI) | 7494 |
Conjugate | CoraLite® Plus 488 Fluorescent Dye |
Excitation/Emission maxima wavelengths | 493 nm / 522 nm |
Form | Liquid |
Purification Method | Antigen affinity purification |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
X-box-binding protein 1 (XBP1), also named as TREB5, is a 261 amino acid protein, which contains one bZIP domain and belongs to the bZIP family. XBP1 localizes in the nucleus and as a transcription factor is essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response. XBP1 has an association with major affective disorder. The molecular weight of protein generated from the spliced XBP1 mRNA is 54 kDa and protein generated from unspliced Xbp1 mRNA is 33 kDa.
Protocols
Product Specific Protocols | |
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FC protocol for CL Plus 488 XBP-1U specific antibody CL488-25997 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |