Validation Data Gallery
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Tested Applications
| Positive WB detected in | human kidney tissue, mouse pancreas tissue |
| Positive IHC detected in | human renal cell carcinoma tissue, human pancreas tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:1000 |
| Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| KD/KO | See 4 publications below |
| WB | See 9 publications below |
| IHC | See 2 publications below |
| IF | See 3 publications below |
| IP | See 3 publications below |
| CoIP | See 2 publications below |
Product Information
13502-1-AP targets USP46 in WB, IHC, IF, IP, CoIP, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | USP46 fusion protein Ag4330 相同性解析による交差性が予測される生物種 |
| Full Name | ubiquitin specific peptidase 46 |
| Calculated molecular weight | 366 aa, 42 kDa |
| Observed molecular weight | 38-42 kDa |
| GenBank accession number | BC037574 |
| Gene Symbol | USP46 |
| Gene ID (NCBI) | 64854 |
| RRID | AB_10642951 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P62068 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for USP46 antibody 13502-1-AP | Download protocol |
| IHC protocol for USP46 antibody 13502-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
J Exp Med USP1-UAF1 deubiquitinase complex stabilizes TBK1 and enhances antiviral responses.
| ||
Biochim Biophys Acta Mol Basis Dis USP46 enhances tamoxifen resistance in breast cancer cells by stabilizing PTBP1 to facilitate glycolysis | ||
Mol Neurobiol Ceftriaxone Modulates Ubiquitination of α-Amino-3-Hydroxy-5-Methyl-4-Isoxazole Propionic Acid Receptors to Improve Long-Term Potentiation Impairment Induced by Exogenous β-Amyloid in a Glutamate Transporter-1 Dependent Manner | ||
Exp Cell Res Ubiquitin-specific peptidase 46 promotes tumor metastasis through stabilizing ENO1 in human esophageal squamous cell carcinoma.
| ||
FEBS Open Bio Proximity-dependent biotinylation reveals an interaction between ubiquitin-specific peptidase 46 and centrosome-related proteins |