Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
15000-1-PBS targets UNKL in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag6990 Product name: Recombinant human UNKL protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-229 aa of BC000150 Sequence: MTCCSQVPPRRRPSLALSPRLDCNGLNGVPGSIWDFVSGSFSPSPSPILSAGPPSSSSASPNGAELARVRRQLDEAKRKIRQWEESWQQVKQVCDAWQREAQEAKERARVADSDRQLALQKKEEVEAQVKQLQEELEGLGVASTLPGLRGCGDIGTIPLPKLHSLQSQLRLDLEAVDGVIFQLRAKQCVACRERAHGAVLRPCQHHILCEPCAATAPECPYCKGQPLQW 相同性解析による交差性が予測される生物種 |
| Full Name | unkempt homolog (Drosophila)-like |
| Calculated molecular weight | 25 kDa |
| Observed molecular weight | 32 kDa, 45 kDa |
| GenBank accession number | BC000150 |
| Gene Symbol | UNKL |
| Gene ID (NCBI) | 64718 |
| RRID | AB_2213189 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9H9P5 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
Putative E3 ubiquitin-protein ligase UNKL was expressed at significantly lower levels in endometrial tumor tissues as compared to the endometrium. Importantly, in human endometrial cancer, primary tumor expression of UNKL was correlated with overall survival in black patients with high mutational burden.