Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
33326-1-PBS targets Tesmin in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag39255 Product name: Recombinant human MTL5 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 158-306 aa of NM_004923.3 Sequence: VEIKEAGGTTTSNNPEEATLQNLLAQESCCKFPSSQELEDASCCSLKKDSNPMVICQLKGGTQMLCIDNSRTRELKALHLVPQYQDQNNYLQSDVPKPMTALVGRFLPASTKLNLITQQLEGALPSVVNGSAFPSGSTLPGPPKITLAG 相同性解析による交差性が予測される生物種 |
| Full Name | metallothionein-like 5, testis-specific (tesmin) |
| Calculated molecular weight | 55kDa，508aa |
| Observed molecular weight | 60 kDa |
| GenBank accession number | NM_004923.3 |
| Gene Symbol | MTL5 |
| Gene ID (NCBI) | 9633 |
| RRID | AB_3742940 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity Purification |
| UNIPROT ID | Q9Y4I5 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
Testis Expressed Metallothionein Like Protein (Tesmin), also known as Metallothionein-Like 5 (MTL5), encodes the metallothionein-like protein owning some characteristics of metallothionein. Tesmin is a 60 kDa protein which has cysteine-rich motifs (CXC domain), characteristic of metallothioneins (MTs). Tesmin was closely related to meiosis in the reproductive process. As a testis-specific protein, the localization of Tesmin changed dynamically with the progression of meiosis in a mouse experiment, the process of which might be responsive to metal stress like cadmium by oxidative stress (Cd), as well as require the involvement of LIN9. So far, the expression of Tesmin in adult humans has been observed in prostate and gastric cancer (PMID: 39229988, PMID: 33281959, PMID: 31059101).