TWEAKR Polyclonal antibody
TWEAKR Polyclonal Antibody for IHC, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
IHC, ELISA
Conjugate
Unconjugated
Cat no : 19836-1-AP
Synonyms
Validation Data Gallery
Tested Applications
Positive IHC detected in | mouse heart tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
Recommended dilution
Application | Dilution |
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Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
Sample-dependent, check data in validation data gallery |
Product Information
19836-1-AP targets TWEAKR in IHC, ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | TWEAKR fusion protein Ag13823 相同性解析による交差性が予測される生物種 |
Full Name | tumor necrosis factor receptor superfamily, member 12A |
Calculated molecular weight | 129 aa, 14 kDa |
GenBank accession number | BC002718 |
Gene symbol | TNFRSF12A |
Gene ID (NCBI) | 51330 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
TweakR (Fn14, TNFRSF12A) is a member of the TNF receptor superfamily which is activated by its ligand, the cytokine TWEAK (TNFSF12). TweakR is the smallest member of the TNFR superfamily . TweakR was first described as an FGF-inducible gene which played a role in fibroblast adhesion and migration . Subsequently, the induction of TweakR expression by other growth factors and/or upon tissue injury was observed in multiple cell types, including hepatocytes, endothelial cells, adipocytes, and cardiomyocytes. (PMID: 23073510, PMID: 24409185)
Protocols
Product Specific Protocols | |
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IHC protocol for TWEAKR antibody 19836-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |