Validation Data Gallery
Tested Applications
| Positive WB detected in | mouse cerebellum tissue, HEK-293 cells, 37℃ incubated mouse brain tissue, unboiled rat brain tissue |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:2000-1:10000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
84019-5-RR targets TRPC3 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | TRPC3 fusion protein Ag13024 相同性解析による交差性が予測される生物種 |
| Full Name | transient receptor potential cation channel, subfamily C, member 3 |
| Calculated molecular weight | 848 aa, 97 kDa |
| Observed molecular weight | 105 kDa, 97 kDa |
| GenBank accession number | BC093682 |
| Gene Symbol | TRPC3 |
| Gene ID (NCBI) | 7222 |
| RRID | AB_3671588 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | Q13507 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
TRPC3 (Short transient receptor potential channel 3), also known as TRP3. It is expected to be located in the cell membrane, which is expressed predominantly in brain and at much lower levels in ovary, colon, small intestine, lung, prostate, placenta and testis. TRPC3 is one of the classical members of the mammalian transient receptor potential (TRP) superfamily of ion channels. TRPC3 is a molecule with intriguing sensory features including the direct recognition of and activation by diacylglycerols (DAG). Although TRPC3 channels are ubiquitously expressed, they appear to control functions of the cardiovascular system and the brain in a highly specific manner. Moreover, a role of TRPC3 in immunity, cancer, and tissue remodeling has been proposed, generating much interest in TRPC3 as a target for pharmacological intervention. The molecular weight of TRPC3 is 105 kDa, and it can recognize another isoform. (PMID: 30037143)
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for TRPC3 antibody 84019-5-RR | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |