Validation Data Gallery
Tested Applications
| Positive WB detected in | mouse heart tissue, rat heart tissue |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:2000-1:12000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
26607-1-AP targets TRDN in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag24294 Product name: Recombinant human TRDN protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 75-293 aa of BC139910 Sequence: NFSASSIAKIGSDPLKLVRDAMEETTDWIYGFFSLLSDIISSEDEEDDDGDEDSDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEKGKEKVREKEKPEKKATHKEKIEKKEKPETKTVAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSKPKEKEDKEKAAVSKHEQKGQSPAIPPPLPTEQASRPTPASPALEGKY 相同性解析による交差性が予測される生物種 |
| Full Name | triadin |
| Calculated molecular weight | 729 aa, 82 kDa |
| Observed molecular weight | 39 kDa |
| GenBank accession number | BC139910 |
| Gene Symbol | TRDN |
| Gene ID (NCBI) | 10345 |
| RRID | AB_3085888 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q13061 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
TRDN is a complete transmembrane protein connecting the sarcoplasmic reticulum, which has the function of triggering excitation-contraction coupling of skeletal muscle and heart and regulating heart rate. TRDN is significantly expressed in heart and skeletal muscle. Mutations in triadin can lead to malignant ventricular arrhythmias (PMID:33692971).
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for TRDN antibody 26607-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |