Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
20752-1-PBS targets TRAPPC5 in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag13185 Product name: Recombinant human TRAPPC5 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-188 aa of BC042161 Sequence: MEARFTRGKSALLERALARPRTEVSLSAFALLFSELVQHCQSRVFSVAELQSRLAALGRQVGARVLDALVAREKGARRETKVLGALLFVKGAVWKALFGKEADKLEQANDDARTFYIIEREPLINTYISVPKENSTLNCASFTAGIVEAVLTHSGFPAKVTAHWHKGTTLMIKFEEAVIARDRALEGR 相同性解析による交差性が予測される生物種 |
| Full Name | trafficking protein particle complex 5 |
| Calculated molecular weight | 188 aa, 21 kDa |
| Observed molecular weight | 21-23 kDa |
| GenBank accession number | BC042161 |
| Gene Symbol | TRAPPC5 |
| Gene ID (NCBI) | 126003 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q8IUR0 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
Transport protein particle (TRAPP, also known as trafficking protein particle), a multimeric guanine nucleotide-exchange factor, regulates multiple membrane trafficking pathways (PMID: 20966969). TRAPPC5 is a component of the TRAPP complexes and is involved in processes such as intracellular vesicle transport. In hepatocellular carcinoma, upregulated expression of TRAPPC5 can enhance cancer cell proliferation, migration, invasion and epithelial-mesenchymal transition (EMT) and promote tumorigenesis (PMID: 35425722).