Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
12404-1-PBS targets TPST1 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag3093 Product name: Recombinant human TPST1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 30-371 aa of BC013188 Sequence: ECHHRIEERSQPVKLESTRTTVRTGLDLKANKTFAYHKDMPLIFIGGVPRSGTTLMRAMLDAHPDIRCGEETRVIPRILALKQMWSRSSKEKIRLDEAGVTDEVLDSAMQAFLLEIIVKHGEPAPYLCNKDPFALKSLTYLSRLFPNAKFLLMVRDGRASVHSMISRKVTIAGFDLNSYRDCLTKWNRAIETMYNQCMEVGYKKCMLVHYEQLVLHPERWMRTLLKFLQIPWNHSVLHHEEMIGKAGGVSLSKVERSTDQVIKPVNVGALSKWVGKIPPDVLQDMAVIAPMLAKLGYDPYANPPNYGKPDPKIIENTRRVYKGEFQLPDFLKEKPQTEQVE 相同性解析による交差性が予測される生物種 |
| Full Name | tyrosylprotein sulfotransferase 1 |
| Calculated molecular weight | 370 aa, 42 kDa |
| Observed molecular weight | 42 kDa |
| GenBank accession number | BC013188 |
| Gene Symbol | TPST1 |
| Gene ID (NCBI) | 8460 |
| RRID | AB_2877855 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | O60507 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
TPST1 is a human tyrosylprotein sulfotransferase that uses 3′phosphoadenosine-5′phosphosulfate (PAPS) to transfer the sulfate moiety to proteins predominantly designated for secretion. High TPST1 expression was linked with clinicopathological characteristics and unfavorable prognosis of HNSC patients (PMID: 16859706). In lung cancer, TPST1 expression was associated with the tumor-node metastasis (TNM) stage and lymph node metastasis, suggesting that it may be a useful prognostic indicator for lung cancer patients (PMID: 18243191, 17028309).