Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
51017-1-PBS targets TOM1L1 in WB, ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag0502 Product name: Recombinant human TOM1L1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 381-1/1 of BC029396 Sequence: 相同性解析による交差性が予測される生物種 |
| Full Name | target of myb1 (chicken)-like 1 |
| Calculated molecular weight | 476 aa, 53 kDa |
| Observed molecular weight | 53 kDa |
| GenBank accession number | BC029396 |
| Gene Symbol | TOM1L1 |
| Gene ID (NCBI) | 10040 |
| RRID | AB_2207419 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | O75674 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
Target of Myb-like protein 1 (TOM1L1), also known as Srcasm, belongs to the Tom family. TOM1L1 encodes an adaptor protein characterized by an N-terminal VHS domain and a central GAT domain, which facilitates interactions with clathrin and components of the endosomal sorting machinery. Functionally, TOM1L1 serves as a substrate for Src family kinases, playing a regulatory role in growth factor signaling and membrane trafficking. It is involved in endocytosis, signal transduction, and the negative regulation of mitotic cell division. (PMID: 17977829, PMID: 26899482, PMID: 35238864, PMID: 39548458)