Validation Data Gallery
Tested Applications
| Positive WB detected in | K-562 cells, U2OS cells, SiHa cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:8000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
32692-1-AP targets TMCO7 in WB, ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag38358 Product name: Recombinant human TMCO7 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 331-665 aa of BC015617 Sequence: MAAQSTLNRKDLEGKIEEQQQTSHERPTDVAHSHLEQQQSHETAPQTGLQSNAPIIPQGVNEPSTTTSQKSGSVTTEQLQEVLLSAYDPQIPTRAAALRTLSHWIEQREAKALEMQEKLLKIFLENLEHEDTFVYLSAIQGVALLSDVYPEKILPDLLAQYDSSKDKHTPETRMKVGEVLMRIVRALGDMVSKYREPLIHTFLRGVRDPDGAHRASSLANLGELCQRLDFLLGSVVHEVTACLIAVAKTDGEVQVRRAAIHVVVLLLRGLSQKATEVLSAVLKDLYHLLKHVVCLEPDDVAKLHAQLALEELDDIMKNFLFPPQKLEKKIMVLP 相同性解析による交差性が予測される生物種 |
| Full Name | transmembrane and coiled-coil domains 7 |
| Calculated molecular weight | 1094 aa, 120 kDa |
| Observed molecular weight | 120 kDa |
| GenBank accession number | BC015617 |
| Gene Symbol | TMCO7 |
| Gene ID (NCBI) | 79613 |
| RRID | AB_3742709 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity Purification |
| UNIPROT ID | Q9C0B7 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
TMCO7, also known as transmembrane and coiled-coil domain 7 or TANGO6. MCO7 is predicted to play a role in protein secretion and is considered an integral component of the membrane. TMCO7 has been implicated in leukemia, with ongoing research focusing on validating its role using in vivo leukemic mouse models and protein localization studies. It is being explored as a potential therapeutic target for acute myeloid leukemia (AML).
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for TMCO7 antibody 32692-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |