Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
26994-1-PBS targets TCTEX1D2 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag25770 Product name: Recombinant human TCTEX1D2 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-142 aa of BC021177 Sequence: MATSIGVSFSVGDGVPEAEKNAGEPENTYILRPVFQQRFRPSVVKDCIHAVLKEGLANAEYSPEEMPQLTKHLSENIKDKLKEMGFDRYKMVVQVVIGEQRGEGVFMASRCFWDADTDNYTHDVFMNDSLFCVVAAFGCFYY 相同性解析による交差性が予測される生物種 |
| Full Name | Tctex1 domain containing 2 |
| Observed molecular weight | 16 kDa |
| GenBank accession number | BC021177 |
| Gene Symbol | TCTEX1D2 |
| Gene ID (NCBI) | 255758 |
| RRID | AB_2890214 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q8WW35 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
DYNLT2B also known as TCTEX1D2, belongs to the dynein family and is required for proper retrograde ciliary transport(PMID: 29742051). TCTEX1D2 functions as a light chain that appears to stabilize the retrograde IFT dynein complex. Mutations in TCTEX1D2 are associated with Short-rib thoracic dysplasia 17 with or without polydactyly (SRTD17)( PMID: 26044572).