Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
98526-1-PBS targets TCR Vγ9Vδ2 in FC applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
Recombinant protein 相同性解析による交差性が予測される生物種 |
| Full Name | TCR Vγ9Vδ2 |
| Gene Symbol | |
| Gene ID (NCBI) | |
| RRID | AB_3746154 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Protein A purification |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
TCR Vγ9Vδ2 refers to a specific type of T cell receptor (TCR) found on a subset of gamma delta (γδ) T cells called Vγ9Vδ2 T cells. These cells are a major population of human γδ T cells in the blood and are characterized by the expression of a unique TCR that recognizes phosphoantigens (pAg). Vγ9Vδ2 T cell activation is tightly regulated by a variety of activating or inhibitory receptors which are specific for constitutively expressed or stress-modulated ligands (PMID: 20447835, 40040716). The most effective TCR Vg9Vd2-mediated cell activation relies on TCR interaction with BTN3A1, BTN3A2, and BTN2A1 molecules expressed by target cells (PMID: 25566259).