Validation Data Gallery
Tested Applications
| Positive FC detected in | human PBMCs |
Recommended dilution
| Application | Dilution |
|---|---|
| Flow Cytometry (FC) | FC : 0.25 ug per 10^6 cells in a 100 µl suspension |
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
98527-1-RR targets TCR Vγ5Vδ1 in FC applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
Recombinant protein 相同性解析による交差性が予測される生物種 |
| Full Name | TCR Vγ5Vδ1 |
| Gene Symbol | |
| Gene ID (NCBI) | |
| RRID | AB_3746155 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Protein A purification |
| Storage Buffer | PBS with 0.09% sodium azide{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at 2 - 8°C. Stable for one year after shipment. |
Background Information
TCR Vγ5Vδ1 refers to a specific type of T cell receptor (TCR) found on γδ T cells. These cells are a distinct subset of T lymphocytes that play a role in immune responses, particularly in maintaining tissue integrity and responding to stress signals. The Vγ5Vδ1 TCR is uniquely expressed on a population of T cells called dendritic epidermal T cells (DETCs) that reside in the epidermis (PMID: 35260830, 35031803). The Vγ5Vδ1 TCR-CD3 complex forms an asymmetric dimer, with the Vγ5 domains of each protomer interacting to create a back-to-back structure. This dimeric form is essential for T cell activation (PMID: 38657677).
Protocols
| Product Specific Protocols | |
|---|---|
| FC protocol for TCR Vγ5Vδ1 antibody 98527-1-RR | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |