Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
20663-1-PBS targets Stabilin-1 in IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
Peptide 相同性解析による交差性が予測される生物種 |
| Full Name | stabilin 1 |
| Calculated molecular weight | 276 kDa |
| GenBank accession number | NM_015136 |
| Gene Symbol | STAB1 |
| Gene ID (NCBI) | 23166 |
| RRID | AB_2878721 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9NY15 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
Stabilin-1, also known as FEEL-1 or CLEVER-1, is a large type I transmembrane scavenger receptor primarily expressed on tissue-resident macrophages and lymphatic sinus endothelial cells. It functions in endocytosis, intracellular sorting, phagocytosis, and cell adhesion, and is highly upregulated in alternatively activated macrophages by IL-4 and dexamethasone. The protein localizes to endosomes and the trans-Golgi network, playing essential roles in immune regulation, pathogen clearance, and tissue homeostasis. (PMID: 16989725)




